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Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A | Science
Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering | Beilstein Journal of Organic Chemistry

A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli | Proceedings of the National Academy of Sciences

2020, Highlights

Bacillimidazoles A−F, Imidazolium-Containing Compounds Isolated from a Marine Bacillus | Mar. Drugs

2022

Nostopeptolide plays a governing role during cellular differentiation of the symbiotic cyanobacterium Nostoc punctiforme | Proceedings of the National Academy of Sciences

2015

Phylogeny-guided discovery of a promiscuous P450 macrocyclase for the production of diverse atropopeptides | Chemical Science

2025, Highlights

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We keep you up to date about our latest publications and developments on Twitter. Follow us @Helfrich_lab

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natprodreports Nat. Prod. Reports @natprodreports ·
8 Apr

🔓Don't miss this #OpenAccess article in our latest issue by Eric Helfrich et al. @goetheuni looking at the role and mechanisms of canonical and non-canonical tailoring enzymes in bacterial terpenoid biosynthesis

Check it out in full on our website👇

HelfrichLab

Explorative Natural Product Genomics.

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